To analyze the influence of stone column installation on the enhancement of soft ground and to reveal the physical aspects of the soil-pile interaction (SPI) mechanism, the stone column installation process is fully simulated by the three-dimensional continuous-discrete coupling (CDC) method for the first time.The stone column is simulated by parti
Preventing disability in older adults with mild cognitive impairment: A Strategy Training intervention study
Non-pharmacological interventions designed to change cognitive function in older adults with Mild Cognitive Impairment have shown mixed results.Few studied interventions directly address preclinical disability.Slowing changes in disability Laundry Centre are critical preserve independence and health related quality of life in older adults with Mild
Helper NLR immune protein NRC3 evolved to evade inhibition by a cyst nematode virulence effector.
Parasites can counteract host immunity by suppressing nucleotide binding and leucine-rich repeat (NLR) proteins that function as immune receptors.We previously showed that a cyst nematode virulence effector SPRYSEC15 (SS15) binds and inhibits oligomerisation of helper NLR proteins in the expanded NRC1/2/3 clade by preventing intramolecular rearrang